What is a Thyroid Profile Test?
The Thyroid Profile Test is a blood test that evaluates the thyroid gland’s activity, which is an important component of the endocrine system that regulates metabolism and energy production. It is also known as the Thyroid panel. (Source)
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The Thyroid Profile Test is made up of multiple different tests, such as:
1. TSH (Thyroid Stimulating Hormone)
Thyroid-stimulating hormone (TSH) causes your thyroid to release hormones that affect your body’s metabolism. TSH values that are too high or too low typically point to hypothyroidism or hyperthyroidism, respectively.
What are the normal values of TSH?
0.4 – 4.0 mIU/L
What does low TSH indicate?
This indicates that the thyroid gland is hyperactive. This could be due to Graves’ illness or excessive thyroid hormone supplementation.
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What does high TSH indicate?
This indicates that the thyroid gland is hyperactive. This could be due to Graves’ illness or excessive thyroid hormone supplementation.
2. T3 (Triiodothyronine)
T3 is one of the two primary thyroid hormones that regulate metabolism. Thyroid hormone in its active form. Elevated levels could indicate hyperthyroidism, whilst low levels could indicate hypothyroidism.
What are the normal values of T3?
2.3 – 4.2 pg/mL
What does low T3 indicate?
Low Free T3 levels indicate an underactive thyroid, which may indicate hypothyroidism.
What does high T3 indicate?
High levels of free T3 indicate an overactive thyroid, implying hyperthyroidism.
3. T4 (Thyroxine)
T4 is a major thyroid hormone that is transformed into T3. The unbound, active version of this hormone is measured as free T4. High levels could indicate hyperthyroidism, whilst low levels could indicate hypothyroidism.
What are the normal values of T4?
0.8 – 2.8 ng/dL
What does low T4 indicate?
Low Free T4 levels indicate an underactive thyroid, which may indicate hypothyroidism.
What does high T4 indicate?
High levels of free T4 indicate an overactive thyroid, implying hyperthyroidism.
4. Total T3 (Triiodothyronine) and Total T4 (Thyroxine) tests
These tests determine the total quantity of T3 and T4 in the blood, including bound and unbound forms. They can be used to validate the results of the Free T3 and Free T4 tests.
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What are the normal values of Total T3?
80 – 200 ng/dL
What are the normal values of Total T4?
4.5 – 12.5 µg/dL
What do low and high Total T3 and T4 indicate?
These tests can detect both bound and unbound T3 and T4 forms. Elevated levels indicate hyperthyroidism, whilst low levels indicate hypothyroidism.
5. Thyroid Antibodies (TPOAb and TgAb)
These tests look for antibodies that could target the thyroid gland. Elevated levels can be indicative of autoimmune thyroid disorders such as Hashimoto’s thyroiditis.
What are the normal values of TPOAb?
Less than 35 IU/mL
What are the normal values of TgAb?
Less than 20 IU/mL
What do low TPOAb and TgAb indicate?
This indicates that there are few or no antibodies that target the thyroid peroxidase enzyme.
What do high TPOAb and TgAb indicate?
High levels of antibodies indicate the presence of antibodies that may target the thyroid gland. This points to an autoimmune thyroid disorder such as Hashimoto’s thyroiditis.
6. Reverse T3 (rT3)
This test detects a dormant version of T3. Elevated levels are common in cases of acute sickness or stress.
What are the normal values of T3 (rT3)?
9 – 27 ng/dL
What does low Reverse T3 (rT3) indicate?
A low Reverse T3 (rT3) level is considered to be within the normal range.
What does high Reverse T3 (rT3) indicate?
High rT3 levels can suggest “euthyroid sick syndrome” or other non-thyroidal disorders. It is a reaction to a serious disease or stress.
An overactive and underactive thyroid can disrupt daily routines and reduce quality of life. If you experience thyroid disease symptoms, a Thyroid Profile test can determine what’s causing them so your provider can offer treatment.
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